Infertility affects approximately 15% of couples worldwide, with male infertility contributing to about 50% of cases. Male infertility is the man’s inability to cause pregnancy in a fertile female partner. With the advancement of medical technology, IVF procedures have been developed to help couples struggling with infertility.

This article will discuss some of the latest IVF procedures for male infertility.

Diagnostic procedures for male infertility:

Before any treatment can be administered, a thorough diagnosis must be conducted. This diagnosis includes several tests such as semen analysis, sperm DNA fragmentation testing, hormonal testing, and genetic testing. Semen analysis is the most common test for male infertility, which measures the quality and quantity of sperm produced. Sperm DNA fragmentation testing identifies if the DNA in the sperm is damaged, which affects fertilization and embryo development. Hormonal testing determines if hormonal imbalances contribute to male infertility. Genetic testing helps identify genetic conditions that could be the cause of infertility.

IVF procedures for male infertility:

Intracytoplasmic sperm injection (ICSI) is the most commonly used IVF procedure for male infertility. During ICSI, a single sperm is selected and injected directly into the egg, bypassing any natural barriers that may prevent fertilization. ICSI is particularly useful for couples where the male partner has a low sperm count, abnormal sperm morphology or poor sperm motility.

Testicular sperm extraction (TESE) is a surgical procedure used to extract sperm from the testicles directly. This procedure is typically recommended for men with no sperm in their semen, a condition known as azoospermia. During the TESE procedure, a small incision is made in the testicles, and a small amount of testicular tissue is extracted. The extracted tissue is then analyzed to determine if sperm is present, and if so, it is used for fertilization through ICSI.

An alternative surgical method for retrieving sperm from the male reproductive system is percutaneous epididymal sperm aspiration (PESA), which involves extracting sperm from the epididymis – a tube that connects the vas deferens to the testicles. PESA is also recommended for men with azoospermia. During the PESA procedure, a needle is inserted through the scrotum into the epididymis, and a small amount of fluid is extracted. The fluid is then analyzed to determine if sperm is present, and if so, it is used for fertilization through ICSI.

Electroejaculation (EEJ) is a procedure that involves using electrical stimulation to extract sperm from the prostate gland. This procedure is recommended for men with spinal cord injuries or nerve damage that prevent them from ejaculating normally. During the EEJ procedure, a probe is inserted into the rectum, and the electrical current is used to stimulate the prostate gland, causing ejaculation. The semen is then collected and analyzed for viable sperm, which can be used for fertilization through ICSI.

Advanced techniques in IVF for male infertility:

A more advanced form of ICSI is Intracytoplasmic morphologically selected sperm injection (IMSI). It involves selecting the best sperm based on their shape and morphology to increase the chances of fertilization. Physiological intracytoplasmic sperm injection (PICSI) uses a special dish coated with a substance that mimics the environment of the female reproductive tract. The dish helps select the best sperm based on their ability to bind to the coating. Magnetic-activated cell sorting (MACS) is a technique used to select healthy sperm by removing the ones with DNA damage. Endometrial receptivity array (ERA) is a test used to determine the best time for embryo transfer based on the receptivity of the endometrium. The EmbryoScope is an advanced incubator used to continuously monitor embryos’ development, providing a more stable environment for their growth.


Infertility is a complex issue, and male infertility is one of the contributing factors. However, with the advancement of medical technology, several IVF procedures have been developed to address male infertility. It is crucial to seek help from the best IVF doctor in Noida to ensure that the right diagnosis and treatment are provided. The IVF Clinic in Noida has highly trained and experienced doctors who can provide comprehensive male infertility treatments. By using advanced techniques, IVF Clinic in Noida can help couples struggling with male infertility achieve their dream of having a baby.